Reference Number: JO-1910-438855
Clinical Pharmacologist/Clinical Scientist
Rate: Negotiable
Job Type: Permanent
Location: Slough

Senior Scientist – Nonclinical PK-PD NBE
Research & Early Development
Location: Berkshire
Competitive Salary, Car allowance + Benefits

My client is a global biopharmaceutical company whose ethos is centered around
improving the lives of people living with severe diseases of the immune system and the central nervous system. They aim to use innovative approaches to drive innovation and offer new approaches with the hope of a new generation of therapies that will help to transform lives.

They are looking for an experienced Senior Pre-Clinical Scientist/Clinical Pharmacologist to work within the DMPK function of their Development Sciences team. This unit operates collaboratively with cross-functional teams to deliver strategy and support in bioanalysis, immunogenicity, safety, pathology, and regulatory activities. They are looking for an experienced and enthusiastic individual with Preclinical PKPD experience to join them.


Develop and drive the nonclinical PKPD strategy for projects.
Ensure translation from in vitro data and in vivo non-clinical studies to
prediction of efficacy and safety in patients
Initiate and engage in multi-functional collaborations to facilitate the
advancement of drug candidates and build a thorough knowledge of drug
pharmacology and PKPD, leading to quantitative translation to the clinic
Build PKPD models of sufficient complexity to allow hypothesis testing and
inform decision-making.
Provide scientific and technical input, expertise and leadership to Non-clinical
PKPD group, project teams, and Development Sciences

Candidate Requirements:

PhD in relevant discipline (pharmacology, bioengineering,
pharmacokinetics/pharmacodynamics, etc.)
Good understanding of pharmacology and pharmacologic processes related to
disease and drug mechanisms
Expertise and proven application of PKPD methods and concepts in support of
drug discovery and development; systems modelling experience would be
Demonstrated experience in developing and executing effective nonclinical
PKPD strategies from early discovery through to clinic
Innovative, self-motivated, team-oriented scientist with good written and verbal
communication skills, able to handle multiple-projects
Experience working within a matrix environment with a wide range of internal
stakeholders including Non-Clinical Safety, Bioanalysis, Clinical Pharmacology
and Translational Medicine.

If this role is of interest, please call George on 0118 959 4990 or email your cv to george@clinicalprofessionals.co.uk

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