Reference Number: JO-1909-436833
Formulation Development – Research Associate
Job Type: Permanent
If you are inspired by developing your career in a stimulating environment where you can make a profound difference to the healthcare of patients, my client can offer exceptional careers for exceptional people. Based on an established Bioscience campus in Cambridge, you will have the opportunity to work with smarter science, unique technologies and highly experienced scientific leaders.
Our client is looking for a highly skilled formulation scientist to support the early stage formulation development of their pipeline. Reporting to the team leader of Drug Product Development, this is an exciting opportunity to work in a dynamic and fast-growing environment within the Biopharmaceutical Development (BPD) and build the drug product strategy to enable pre-clinical and clinical studies.
You will be responsible for generating data packages to drive the drug product development for the client’s pipeline and help building a seamless internal capability by working closely with cell line, cell culture, downstream and analytical teams.
You will be involved in a range of activities such as:
Perform pre-formulation and formulation studies, force degradation, accelerated and real time studies
Design, conduct and interpret analytical assays (e.g. chromatographic and electrophoretic methods, light scattering) to support screening stages, product quality analysis and stability testing
Contribute to establish new stability indicating assays
Provide concise data summary and present outcome to key stakeholders
Education & Experience
Educated to at least degree level in an Analytical/formulation science, or another relevant degree
Previous, relevant bench-based laboratory experience in drug product development of biomolecules
Experience in protein analytics (e.g. HPLC, SDS PAGE, CE, DLS, SLS) and routine laboratory procedures (pH, conductivity, spectrometry)
Proven, demonstrable experience in liquid formulation of biologics, excipients screening and stability testing
Experience in formulation of bispecific antibodies and non-conventional formats (desirable)
Experience in lyophilization of biologics (desirable)
Experience in drug product fill/finish and labelling processes (desirable)
Skills & Knowledge
In-depth understanding of protein biochemistry and/or protein biophysics
Ability to work to tight deadlines, troubleshoot effectively and respond quickly to changes in priority
Methodical, organised with an aptitude for detail
Ability to work closely with others, encourage good team spirit, motivate a multi-skilled team to higher goals and demonstrate initiative as required
A flexible and willing attitude with the desire to continually improve and develop
Can you see yourself being part of a company that celebrates diversity and believes that better thinking and decisions come from wider experience? If the answer is yes and you have a desire to be an integral part of a dynamic team, we would be keen to hear from you. In the first instance, please send your CV to Matthew Walsh: firstname.lastname@example.org . We endeavour to come back to you within 24 hours of CV submission.