Reference Number: JO-2002-445578
Research Scientist I/II, in vivo Pharmacology
Rate: Negotiable
Job Type: Permanent
Location: Cambridge

If you are inspired by developing your career in a stimulating environment where you can make a profound difference to the healthcare of patients, my client can offer exceptional careers for exceptional people. Based on an established Bioscience campus in Cambridge, you will have the opportunity to work with smarter science, unique technologies and highly experienced scientific leaders.

Reporting to the Director of Pharmacology & Translational Sciences, our client is looking for a Research Scientist I/II, to design and run work streams focussing on the identification and characterisation of the mechanism of action of lead antibodies from our immune-oncology projects to inform decisions on progression of candidate molecules towards development.

Key Responsibilities

Design and run the in vivo pharmacology/oncology studies
Perform regulated in vivo experimental procedures covered by Home Office licences
Perform tissue culture in support of studies
Harvest experimental tissues
Perform ex vivo analysis
Analysis and interpretation of data and reporting key outcomes to the project team and management
Ensure accurate recording of and reporting of data
Actively engage across the organization

As part of the team you will be required to participate in weekend/public holiday rota to perform essential animal check-ups and procedures.

Job Requirements

Education & Experience

PhD or equivalent industrial experience with proven track record evidenced by first author publications / patent authorship
Experience with tumour models (preferred)
Proven track record in delivery of molecules into development
Personal Home Office Licence Modules A-C & extensive experience with the relevant procedures involved
Experience of contributing to and following SOPs

Skills & Knowledge

Ability to define individual protocols and experimental blocks of work to answer key questions around pharmacology (PK/PD), immunology (mechanism of action) to guide project team decisions
Multiplexed ex-vivo analytical techniques including FACs, RNAseq, cytokine analysis
Ability to analyse and report on large datasets
Confidence with tissue culture
Awareness of A[SP]A and 3Rs
Knowledge of relevant Health and Safety legislation


Ability to keep neat and accurate records including using computerized systems
Flexible and able to work independently with a degree of autonomy and ownership
Ability to work effectively under pressure with conflicting demands
Effective at communicating and liaising at all levels
Ability to engage wider team with strategy, plans and novel ideas
A team player attitude with proven negotiation skills

Can you see yourself being part of a company that celebrates diversity and believes that better thinking and decisions come from wider experience? If the answer is yes and you have a desire to be an integral part of a dynamic team, we would be keen to hear from you. In the first instance, please send your CV to Matthew Walsh: matt@scientificprofessionals.com . We endeavour to come back to you within 24 hours of CV submission.

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