Novartis’ Afinitor Approved for Breast Cancer by FDA

Novartis announced on Friday that they have received approval from US regulators for Afinitor as a treatment for advanced breast cancer. The US Food and Drug Administration (FDA) have given the thumbs up to Afinitor (everolimus) for use with Pfizer’s Aromasin (exemestane) to treat certain postmenopausal women with advanced hormone-receptor positive, HER2-negative breast cancer.  The

Continue Reading

Eisai’s Halaven Receives Final Draft “No” From NICE

In final draft guidance given yesterday, the National Institute for Health and Clinical Excellence (NICE) announced that they are not recommending Eisai’s Halaven (eribulin) for the treatment of locally-advanced or metastatic breast cancer in people whose disease has progressed after at least two chemotherapeutic regimens for advanced disease. Although the evidence shown to NICE’s independent

Continue Reading

NICE Reject Breast Cancer Drug Faslodex

England and Wales’ cost watchdog, NICE, yesterday reiterated their assessment that AstraZeneca’s breast cancer drug Faslodex does not represent good use of NHS funds and has not been proven to be better than current treatments. The National Institute for Health and Clinical Excellence (NICE) has published their  final appraisal determination, saying that they do not

Continue Reading

Roche Reports Positive Herceptin Results

Swiss pharmaceutical company, Roche, yesterday announced that the Phase III HannaH study demonstrated comparable efficacy of a new, investigational subcutaneous formulation of Herceptin (trastuzumab) to the standard intravenous infusion of Herceptin in women with HER2-positive early breast cancer. HannaH is a Phase III, open-label study consisting of 596 women with HER2 positive early breast cancer.

Continue Reading